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SHORT-TERM EFFECT OF LAPAROSCOPIC SLEEVE GASTERECTOMY ON HYPERLIPIDEMIC OBESE PATIENTS
EAES Academy. Elkeleny M. 07/05/22; 362971; P014
Dr. Mostafa Refaie Abdelatty Elkeleny
Dr. Mostafa Refaie Abdelatty Elkeleny
Contributions
Abstract
Background:

Obesity has become a global epidemic and major health problem in the 21st century; Studies have shown that weight loss reduces elevated serum total cholesterol and low-density lipoprotein (LDL) cholesterol and increases high-density lipoprotein (HDL) cholesterol. Laparoscopic sleeve gastrectomy is one of the most recent ways to treat obesity and manage weight loss in overweight patients whose options for weight loss are limited.

Objectives
The aim of this study was to evaluate the short-term effect of laparoscopic sleeve gastrectomy on lipid profile in hyperlipidemic obese patients during the nine months of post- operative care.

Methods
This prospective study was conducted on 50 hyperlipidemic obese candidates of bariatric surgery at Main University Hospital in Alexandria, Egypt from July 2020 to October 2021. Body weight, Body mass index (BMI), Waist circumference, Fasting and postprandial blood sugar, serum cholesterol, triglyceride, HDL and LDL levels were measured before and one, three, six and nine months following the surgical intervention.

Results:

The mean age of the participants was 33.72-7.95 years. There was significant reduction in BMI, weight, blood sugar, Mean body mass index (BMI) of the patients before surgery was 48.59 - 5.78 kg/m2, which was lowered to 32.58 -3.91 kg/m2 nine months after the intervention. Assessments showed a statistically significant increase in the serum level of HDL and a statistically significant decrease in the serum level of triglycerides, the serum level of total cholesterol and LDL. Moreover, results showed a positive correlation between lipid profile changes after LSG and preoperative variations in Age, BMI and Diabetic condition.

Conclusion:
Laparoscopic sleeve gastrectomy reduces body mass and leads to improvement in glucose and lipid metabolism and lipid profile changes: decrease in Total Cholesterol, Triglyceride and LDL cholesterol and increase in HDL cholesterol in a significant way.
Background:

Obesity has become a global epidemic and major health problem in the 21st century; Studies have shown that weight loss reduces elevated serum total cholesterol and low-density lipoprotein (LDL) cholesterol and increases high-density lipoprotein (HDL) cholesterol. Laparoscopic sleeve gastrectomy is one of the most recent ways to treat obesity and manage weight loss in overweight patients whose options for weight loss are limited.

Objectives
The aim of this study was to evaluate the short-term effect of laparoscopic sleeve gastrectomy on lipid profile in hyperlipidemic obese patients during the nine months of post- operative care.

Methods
This prospective study was conducted on 50 hyperlipidemic obese candidates of bariatric surgery at Main University Hospital in Alexandria, Egypt from July 2020 to October 2021. Body weight, Body mass index (BMI), Waist circumference, Fasting and postprandial blood sugar, serum cholesterol, triglyceride, HDL and LDL levels were measured before and one, three, six and nine months following the surgical intervention.

Results:

The mean age of the participants was 33.72-7.95 years. There was significant reduction in BMI, weight, blood sugar, Mean body mass index (BMI) of the patients before surgery was 48.59 - 5.78 kg/m2, which was lowered to 32.58 -3.91 kg/m2 nine months after the intervention. Assessments showed a statistically significant increase in the serum level of HDL and a statistically significant decrease in the serum level of triglycerides, the serum level of total cholesterol and LDL. Moreover, results showed a positive correlation between lipid profile changes after LSG and preoperative variations in Age, BMI and Diabetic condition.

Conclusion:
Laparoscopic sleeve gastrectomy reduces body mass and leads to improvement in glucose and lipid metabolism and lipid profile changes: decrease in Total Cholesterol, Triglyceride and LDL cholesterol and increase in HDL cholesterol in a significant way.

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