EAES Academy

Aims:

In colonic lipoma, colonoscopic biopsy is not recommended in patients suspected of colonic lipoma because the lesion is beneath the normal mucosa. The exat diagnosis still mainly relies on pathologic examaination. In addition, biopsy may increase the risks of bleeding and perforation.The aim of this paper was to report and discuss the safety of endoscopic resection for accurate diagnosis in patients with colonic lipomas.
Methods:

The patients enrolled in this study were five patients with colonic lipoma who underwent endoscopic partial resection. All medical records, including characteristics of the patients, lipomas, complications, were retrospectively reviewed.
Results:

The five patients were all women, with a mean age of 65.8 years (range, 54-78 years). Location of the colonic lipoma was 2 in cecum, 2 in ascending colon, and 1 in sigmoid colon. The tumor shape was all submucosal tumors. All detected tumors were removed by endoscopic partial resection after submucosal injection of epinephrine-saline mixture 1:100 000. The endoscopic mean size of tumors was 13.4 mm (range, 10-20 mm). The pathologically measured mean size of the resected specimens was 8.6 mm (range, 5-10 mm). Bleeding prophylaxis was performed in 2 cases by applying a hemoclip Of the five patients, 2 patients were admitted. Endoscopic resection in all cases was performed without any complications. Histopathological examination of the all resected tumor revealed mature adipose tissue in submucosal layer, and there was no evidence of malignancy. It was diagnosed as a submocosal lipoma.
Conclusion:
Endoscopic resection is considered to be a relatively safe and useful method for diagnosis and treatment of colonic lipoma.