Interventional Sonography for the Diagnosis of Pancreatic Disease
EAES Academy. Muradian K. 07/05/22; 363070; P115
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Abstract
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Introduction:
The level of oncological diseases is constantly growing all over the world. Therefore, early diagnosis and treatment of oncological diseases is a top priority for medical institutions.
Aim. Improving the results of oncological diseases diagnostics by introducing the pancreatic neoplasm ultrasound-guided biopsy technique.
Materials and methods. A clinical and statistical analysis of the results of diagnosing pancreatic neoplasms was carried out in 106 patients treated at the Military Medical Clinical Center of the Southern Region of Ukraine in the period from 2014 to 2021. Patients with pancreatic neoplasms in the comparison groups underwent minimally invasive diagnostic operations: ultrasound-guided percutaneous fine-needle aspiration biopsy - 13, ultrasound-guided percutaneous core-needle biopsy - 56, biopsy during diagnostic laparoscopy - 37.
Results:
According to the results of histopathological examination, in 85 (80.2%) cases, signs of carcinoma or ductal carcinoma of the pancreas of varying degrees of differentiation were revealed, in 21 (19.8%) cases, the morphological picture was characteristic of indurative pancreatitis without signs of a malignant neoplastic process. In 6 cases, upon receipt of a pathological and histological conclusion as a benign process (when CT signs of a malignant neoplasm of the pancreas were found), an additional biopsy was performed at other points. In all cases, the diagnosis – pseudotumorous pancreatitis was confirmed again by histopathological examination and immunohistochemical examination, which in turn influenced the choice of further treatment tactics for patients.
In 23 cases, chemotherapy after a biopsy of a pancreatic neoplasm, followed by an immunohistochemical study and detection of sensitivity to chemotherapy drugs, was the final amount of treatment. In other cases, when a malignant formation of the pancreas was detected, surgical treatment of varying severity was performed. In 100% of cases, the histopathological conclusion of the postoperative material coincided with the results of biopsy. There were no complications during the procedures of biopsy.
Conclusions. Ultrasound-guided percutaneous core-needle biopsy is a safe minimally invasive procedure and is highly informative and effective in the treatment of patients with pancreatic diseases. This method helps to reduce the number of more traumatic diagnostic methods that require hospitalization and general anesthesia, which leads to the fastest recovery of patients.
The level of oncological diseases is constantly growing all over the world. Therefore, early diagnosis and treatment of oncological diseases is a top priority for medical institutions.
Aim. Improving the results of oncological diseases diagnostics by introducing the pancreatic neoplasm ultrasound-guided biopsy technique.
Materials and methods. A clinical and statistical analysis of the results of diagnosing pancreatic neoplasms was carried out in 106 patients treated at the Military Medical Clinical Center of the Southern Region of Ukraine in the period from 2014 to 2021. Patients with pancreatic neoplasms in the comparison groups underwent minimally invasive diagnostic operations: ultrasound-guided percutaneous fine-needle aspiration biopsy - 13, ultrasound-guided percutaneous core-needle biopsy - 56, biopsy during diagnostic laparoscopy - 37.
Results:
According to the results of histopathological examination, in 85 (80.2%) cases, signs of carcinoma or ductal carcinoma of the pancreas of varying degrees of differentiation were revealed, in 21 (19.8%) cases, the morphological picture was characteristic of indurative pancreatitis without signs of a malignant neoplastic process. In 6 cases, upon receipt of a pathological and histological conclusion as a benign process (when CT signs of a malignant neoplasm of the pancreas were found), an additional biopsy was performed at other points. In all cases, the diagnosis – pseudotumorous pancreatitis was confirmed again by histopathological examination and immunohistochemical examination, which in turn influenced the choice of further treatment tactics for patients.
In 23 cases, chemotherapy after a biopsy of a pancreatic neoplasm, followed by an immunohistochemical study and detection of sensitivity to chemotherapy drugs, was the final amount of treatment. In other cases, when a malignant formation of the pancreas was detected, surgical treatment of varying severity was performed. In 100% of cases, the histopathological conclusion of the postoperative material coincided with the results of biopsy. There were no complications during the procedures of biopsy.
Conclusions. Ultrasound-guided percutaneous core-needle biopsy is a safe minimally invasive procedure and is highly informative and effective in the treatment of patients with pancreatic diseases. This method helps to reduce the number of more traumatic diagnostic methods that require hospitalization and general anesthesia, which leads to the fastest recovery of patients.
Introduction:
The level of oncological diseases is constantly growing all over the world. Therefore, early diagnosis and treatment of oncological diseases is a top priority for medical institutions.
Aim. Improving the results of oncological diseases diagnostics by introducing the pancreatic neoplasm ultrasound-guided biopsy technique.
Materials and methods. A clinical and statistical analysis of the results of diagnosing pancreatic neoplasms was carried out in 106 patients treated at the Military Medical Clinical Center of the Southern Region of Ukraine in the period from 2014 to 2021. Patients with pancreatic neoplasms in the comparison groups underwent minimally invasive diagnostic operations: ultrasound-guided percutaneous fine-needle aspiration biopsy - 13, ultrasound-guided percutaneous core-needle biopsy - 56, biopsy during diagnostic laparoscopy - 37.
Results:
According to the results of histopathological examination, in 85 (80.2%) cases, signs of carcinoma or ductal carcinoma of the pancreas of varying degrees of differentiation were revealed, in 21 (19.8%) cases, the morphological picture was characteristic of indurative pancreatitis without signs of a malignant neoplastic process. In 6 cases, upon receipt of a pathological and histological conclusion as a benign process (when CT signs of a malignant neoplasm of the pancreas were found), an additional biopsy was performed at other points. In all cases, the diagnosis – pseudotumorous pancreatitis was confirmed again by histopathological examination and immunohistochemical examination, which in turn influenced the choice of further treatment tactics for patients.
In 23 cases, chemotherapy after a biopsy of a pancreatic neoplasm, followed by an immunohistochemical study and detection of sensitivity to chemotherapy drugs, was the final amount of treatment. In other cases, when a malignant formation of the pancreas was detected, surgical treatment of varying severity was performed. In 100% of cases, the histopathological conclusion of the postoperative material coincided with the results of biopsy. There were no complications during the procedures of biopsy.
Conclusions. Ultrasound-guided percutaneous core-needle biopsy is a safe minimally invasive procedure and is highly informative and effective in the treatment of patients with pancreatic diseases. This method helps to reduce the number of more traumatic diagnostic methods that require hospitalization and general anesthesia, which leads to the fastest recovery of patients.
The level of oncological diseases is constantly growing all over the world. Therefore, early diagnosis and treatment of oncological diseases is a top priority for medical institutions.
Aim. Improving the results of oncological diseases diagnostics by introducing the pancreatic neoplasm ultrasound-guided biopsy technique.
Materials and methods. A clinical and statistical analysis of the results of diagnosing pancreatic neoplasms was carried out in 106 patients treated at the Military Medical Clinical Center of the Southern Region of Ukraine in the period from 2014 to 2021. Patients with pancreatic neoplasms in the comparison groups underwent minimally invasive diagnostic operations: ultrasound-guided percutaneous fine-needle aspiration biopsy - 13, ultrasound-guided percutaneous core-needle biopsy - 56, biopsy during diagnostic laparoscopy - 37.
Results:
According to the results of histopathological examination, in 85 (80.2%) cases, signs of carcinoma or ductal carcinoma of the pancreas of varying degrees of differentiation were revealed, in 21 (19.8%) cases, the morphological picture was characteristic of indurative pancreatitis without signs of a malignant neoplastic process. In 6 cases, upon receipt of a pathological and histological conclusion as a benign process (when CT signs of a malignant neoplasm of the pancreas were found), an additional biopsy was performed at other points. In all cases, the diagnosis – pseudotumorous pancreatitis was confirmed again by histopathological examination and immunohistochemical examination, which in turn influenced the choice of further treatment tactics for patients.
In 23 cases, chemotherapy after a biopsy of a pancreatic neoplasm, followed by an immunohistochemical study and detection of sensitivity to chemotherapy drugs, was the final amount of treatment. In other cases, when a malignant formation of the pancreas was detected, surgical treatment of varying severity was performed. In 100% of cases, the histopathological conclusion of the postoperative material coincided with the results of biopsy. There were no complications during the procedures of biopsy.
Conclusions. Ultrasound-guided percutaneous core-needle biopsy is a safe minimally invasive procedure and is highly informative and effective in the treatment of patients with pancreatic diseases. This method helps to reduce the number of more traumatic diagnostic methods that require hospitalization and general anesthesia, which leads to the fastest recovery of patients.
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