A Five year analytic retrospective study of pancreatic cystic neoplasm
EAES Academy. Elkeleny M. 07/05/22; 363075; P120
Dr. Mostafa Refaie Abdelatty Elkeleny
Contributions
Contributions
Abstract
Background- Pancreatic cystic neoplasms (PCNs) are rare disease of the pancreas with varying imaging characteristic and great histological heterogeneity varying from benign, premalignant to overt malignant lesions. Aim- to evaluate the prevalence and types of PCNs, analyzing their clinical characteristics, surgical managements, and outcome post resection.
Methods- this is a retrospective study enrolled 20 patients diagnosed with PCNs at gastrointestinal surgical unit at Alexandria Main University Hospital between January 2015 and December 2019.
Results-in the period evaluated, 20 cases of PCNs were identified and 70% of them were females with the average age at diagnosis of 51±17.1 (range 20-75). Regarding clinical presentations, 90% of the patients were symptomatic with the most common symptom being abdominal pain. Surgical resections were performed in 90% of the patients based on the location of the cysts. Distal pancreatectomy with or without splenectomy was the most common type of surgery performed accounting for 61.1%. Others were pancreaticoduodenectomy in 17%, total pancreatectomy in 11% and enucleation 11%. Intraductal papillary mucinous neoplasm was the most common histological type of PCN accounting for 35%, followed by solid pseudopappilary neoplasm 30%, mucinous cystic neoplasm 25% and serous cystic neoplasm 15%. Regarding post-operative outcome, at least half of the patients experienced one or more post-operative complications, the most common being delayed gastric emptying. Other complications were intraperitoneal collections, chest infection, post-operative pancreatic fistula and exocrine/endocrine pancreatic insufficiency.
Conclusion: At present IPMNs are the most prevalent diagnosed PCNs with notable increase in the frequency of SPEN compared with other types of the cysts that were diagnosed in high frequency at the past. Surgical management is indicated for all symptomatic cysts and cysts suspicious of malignancy
Methods- this is a retrospective study enrolled 20 patients diagnosed with PCNs at gastrointestinal surgical unit at Alexandria Main University Hospital between January 2015 and December 2019.
Results-in the period evaluated, 20 cases of PCNs were identified and 70% of them were females with the average age at diagnosis of 51±17.1 (range 20-75). Regarding clinical presentations, 90% of the patients were symptomatic with the most common symptom being abdominal pain. Surgical resections were performed in 90% of the patients based on the location of the cysts. Distal pancreatectomy with or without splenectomy was the most common type of surgery performed accounting for 61.1%. Others were pancreaticoduodenectomy in 17%, total pancreatectomy in 11% and enucleation 11%. Intraductal papillary mucinous neoplasm was the most common histological type of PCN accounting for 35%, followed by solid pseudopappilary neoplasm 30%, mucinous cystic neoplasm 25% and serous cystic neoplasm 15%. Regarding post-operative outcome, at least half of the patients experienced one or more post-operative complications, the most common being delayed gastric emptying. Other complications were intraperitoneal collections, chest infection, post-operative pancreatic fistula and exocrine/endocrine pancreatic insufficiency.
Conclusion: At present IPMNs are the most prevalent diagnosed PCNs with notable increase in the frequency of SPEN compared with other types of the cysts that were diagnosed in high frequency at the past. Surgical management is indicated for all symptomatic cysts and cysts suspicious of malignancy
Background- Pancreatic cystic neoplasms (PCNs) are rare disease of the pancreas with varying imaging characteristic and great histological heterogeneity varying from benign, premalignant to overt malignant lesions. Aim- to evaluate the prevalence and types of PCNs, analyzing their clinical characteristics, surgical managements, and outcome post resection.
Methods- this is a retrospective study enrolled 20 patients diagnosed with PCNs at gastrointestinal surgical unit at Alexandria Main University Hospital between January 2015 and December 2019.
Results-in the period evaluated, 20 cases of PCNs were identified and 70% of them were females with the average age at diagnosis of 51±17.1 (range 20-75). Regarding clinical presentations, 90% of the patients were symptomatic with the most common symptom being abdominal pain. Surgical resections were performed in 90% of the patients based on the location of the cysts. Distal pancreatectomy with or without splenectomy was the most common type of surgery performed accounting for 61.1%. Others were pancreaticoduodenectomy in 17%, total pancreatectomy in 11% and enucleation 11%. Intraductal papillary mucinous neoplasm was the most common histological type of PCN accounting for 35%, followed by solid pseudopappilary neoplasm 30%, mucinous cystic neoplasm 25% and serous cystic neoplasm 15%. Regarding post-operative outcome, at least half of the patients experienced one or more post-operative complications, the most common being delayed gastric emptying. Other complications were intraperitoneal collections, chest infection, post-operative pancreatic fistula and exocrine/endocrine pancreatic insufficiency.
Conclusion: At present IPMNs are the most prevalent diagnosed PCNs with notable increase in the frequency of SPEN compared with other types of the cysts that were diagnosed in high frequency at the past. Surgical management is indicated for all symptomatic cysts and cysts suspicious of malignancy
Methods- this is a retrospective study enrolled 20 patients diagnosed with PCNs at gastrointestinal surgical unit at Alexandria Main University Hospital between January 2015 and December 2019.
Results-in the period evaluated, 20 cases of PCNs were identified and 70% of them were females with the average age at diagnosis of 51±17.1 (range 20-75). Regarding clinical presentations, 90% of the patients were symptomatic with the most common symptom being abdominal pain. Surgical resections were performed in 90% of the patients based on the location of the cysts. Distal pancreatectomy with or without splenectomy was the most common type of surgery performed accounting for 61.1%. Others were pancreaticoduodenectomy in 17%, total pancreatectomy in 11% and enucleation 11%. Intraductal papillary mucinous neoplasm was the most common histological type of PCN accounting for 35%, followed by solid pseudopappilary neoplasm 30%, mucinous cystic neoplasm 25% and serous cystic neoplasm 15%. Regarding post-operative outcome, at least half of the patients experienced one or more post-operative complications, the most common being delayed gastric emptying. Other complications were intraperitoneal collections, chest infection, post-operative pancreatic fistula and exocrine/endocrine pancreatic insufficiency.
Conclusion: At present IPMNs are the most prevalent diagnosed PCNs with notable increase in the frequency of SPEN compared with other types of the cysts that were diagnosed in high frequency at the past. Surgical management is indicated for all symptomatic cysts and cysts suspicious of malignancy
{{ help_message }}
{{filter}}