Surgical and Oncological Outcomes of Large Gastrointestinal Stromal Tumors Treated by Laparoscopic Resection
EAES Academy. Lin S. 07/05/22; 363172; P217
Dr. Sheng Chieh Lin
Contributions
Contributions
Abstract
Background:
The resection of large gastric gastrointestinal stromal tumors (GISTs) by laparoscopy has been controversial. This study reported the long-term oncological outcome of laparoscopic resection of large (5-8 cm) gastric GISTs in a single center.
Methods. From 2002 to 2018, a consecutive 66 patients with gastric GISTs of 5-8cm were treated at National Taiwan University Hospital. Among them, 30 patients received open surgery, and 36 received laparoscopic surgery. The clinicopathological data, peri-operative and oncological outcomes were compared between groups.
Results:
The clinical demographics including sex, age, BMI, tumor size, tumor locations and ratio of wedge resection were similar between groups. The operation time, blood loss, and post-operative complications, were also similar between groups. The mean hospital stay was shorter in the laparoscopic group (8.8 ± 2.5 days) than in the open group (12.0 ± 8.9 days), though not significantly different. The median follow-up time was 108 ±58 months (97 ±50 in laparoscopic group; 122 ± 64 in open group). All except three patients remain disease-free. One in the open group and two in the laparoscopic group had recurrence of tumor, and they were stable of disease under Imatinib treatment. Eight patients died in non-GIST causes during follow-up.
Conclusion:
Our data showed that laparoscopic surgery for gastric GIST between 5-8 cm was safe and oncologically-feasible.
The resection of large gastric gastrointestinal stromal tumors (GISTs) by laparoscopy has been controversial. This study reported the long-term oncological outcome of laparoscopic resection of large (5-8 cm) gastric GISTs in a single center.
Methods. From 2002 to 2018, a consecutive 66 patients with gastric GISTs of 5-8cm were treated at National Taiwan University Hospital. Among them, 30 patients received open surgery, and 36 received laparoscopic surgery. The clinicopathological data, peri-operative and oncological outcomes were compared between groups.
Results:
The clinical demographics including sex, age, BMI, tumor size, tumor locations and ratio of wedge resection were similar between groups. The operation time, blood loss, and post-operative complications, were also similar between groups. The mean hospital stay was shorter in the laparoscopic group (8.8 ± 2.5 days) than in the open group (12.0 ± 8.9 days), though not significantly different. The median follow-up time was 108 ±58 months (97 ±50 in laparoscopic group; 122 ± 64 in open group). All except three patients remain disease-free. One in the open group and two in the laparoscopic group had recurrence of tumor, and they were stable of disease under Imatinib treatment. Eight patients died in non-GIST causes during follow-up.
Conclusion:
Our data showed that laparoscopic surgery for gastric GIST between 5-8 cm was safe and oncologically-feasible.
Background:
The resection of large gastric gastrointestinal stromal tumors (GISTs) by laparoscopy has been controversial. This study reported the long-term oncological outcome of laparoscopic resection of large (5-8 cm) gastric GISTs in a single center.
Methods. From 2002 to 2018, a consecutive 66 patients with gastric GISTs of 5-8cm were treated at National Taiwan University Hospital. Among them, 30 patients received open surgery, and 36 received laparoscopic surgery. The clinicopathological data, peri-operative and oncological outcomes were compared between groups.
Results:
The clinical demographics including sex, age, BMI, tumor size, tumor locations and ratio of wedge resection were similar between groups. The operation time, blood loss, and post-operative complications, were also similar between groups. The mean hospital stay was shorter in the laparoscopic group (8.8 ± 2.5 days) than in the open group (12.0 ± 8.9 days), though not significantly different. The median follow-up time was 108 ±58 months (97 ±50 in laparoscopic group; 122 ± 64 in open group). All except three patients remain disease-free. One in the open group and two in the laparoscopic group had recurrence of tumor, and they were stable of disease under Imatinib treatment. Eight patients died in non-GIST causes during follow-up.
Conclusion:
Our data showed that laparoscopic surgery for gastric GIST between 5-8 cm was safe and oncologically-feasible.
The resection of large gastric gastrointestinal stromal tumors (GISTs) by laparoscopy has been controversial. This study reported the long-term oncological outcome of laparoscopic resection of large (5-8 cm) gastric GISTs in a single center.
Methods. From 2002 to 2018, a consecutive 66 patients with gastric GISTs of 5-8cm were treated at National Taiwan University Hospital. Among them, 30 patients received open surgery, and 36 received laparoscopic surgery. The clinicopathological data, peri-operative and oncological outcomes were compared between groups.
Results:
The clinical demographics including sex, age, BMI, tumor size, tumor locations and ratio of wedge resection were similar between groups. The operation time, blood loss, and post-operative complications, were also similar between groups. The mean hospital stay was shorter in the laparoscopic group (8.8 ± 2.5 days) than in the open group (12.0 ± 8.9 days), though not significantly different. The median follow-up time was 108 ±58 months (97 ±50 in laparoscopic group; 122 ± 64 in open group). All except three patients remain disease-free. One in the open group and two in the laparoscopic group had recurrence of tumor, and they were stable of disease under Imatinib treatment. Eight patients died in non-GIST causes during follow-up.
Conclusion:
Our data showed that laparoscopic surgery for gastric GIST between 5-8 cm was safe and oncologically-feasible.
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